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Roxane Desjardins Selected Research

Anthrax

6/2010Selective and potent furin inhibitors protect cells from anthrax without significant toxicity.
7/2008Substrate cleavage analysis of furin and related proprotein convertases. A comparative study.
7/2007Targeting host cell furin proprotein convertases as a therapeutic strategy against bacterial toxins and viral pathogens.

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Roxane Desjardins Research Topics

Disease

16Prostatic Neoplasms (Prostate Cancer)
07/2020 - 11/2012
11Neoplasms (Cancer)
07/2020 - 11/2012
3Anthrax
06/2010 - 07/2007
3Influenza in Birds (Avian Flu)
06/2010 - 07/2007
2Human Influenza (Influenza)
01/2014 - 07/2007
2Infections
01/2014 - 07/2007
1Adenocarcinoma
08/2017
1Breast Neoplasms (Breast Cancer)
08/2017
1Hepatocellular Carcinoma (Hepatoma)
11/2016
1Ascites
05/2014
1Ovarian Neoplasms (Ovarian Cancer)
05/2014
1Neoplasm Metastasis (Metastasis)
05/2014
1Septic Shock (Toxic Shock Syndrome)
04/2012
1Cytokine Release Syndrome
04/2012
1Hyperlipoproteinemia Type II (Familial Hypercholesterolemia)
10/2009
1Hyperlipoproteinemia Type III (Broad Beta Disease)
10/2009
1Carcinoma (Carcinomatosis)
01/2009
1Communicable Diseases (Infectious Diseases)
07/2008
1Acute Disease
07/2007
1Hyperinsulinism (Hyperinsulinemia)
03/2007

Drug/Important Bio-Agent (IBA)

15Proprotein Convertases (Pro-Opiomelanocortin Converting Enzyme)IBA
07/2020 - 07/2007
9FurinIBA
12/2018 - 07/2007
7Peptides (Polypeptides)IBA
01/2019 - 07/2007
3EnzymesIBA
07/2020 - 02/2015
3Proteins (Proteins, Gene)FDA Link
05/2014 - 07/2008
3Hemagglutinins (Hemagglutinin)IBA
01/2014 - 07/2007
2Protein Isoforms (Isoforms)IBA
07/2020 - 12/2017
2Serine Proteases (Serine Protease)IBA
01/2018 - 01/2017
2AndrogensIBA
12/2017 - 11/2012
2LDL Receptors (LDL Receptor)IBA
11/2016 - 10/2009
2PeptidomimeticsIBA
02/2015 - 01/2014
2Small Interfering RNA (siRNA)IBA
05/2014 - 01/2014
1E2F Transcription FactorsIBA
07/2020
1Prostate-Specific Antigen (Semenogelase)IBA
01/2019
1ProdrugsIBA
01/2019
1AlbuminsIBA
01/2019
1Serine (L-Serine)FDA Link
12/2018
1Enzyme Precursors (Zymogens)IBA
12/2017
1Biomarkers (Surrogate Marker)IBA
08/2017
13-Mercaptopropionic Acid (3 Mercaptopropionic Acid)IBA
08/2017
1Estrogen ReceptorsIBA
08/2017
1Proprotein Convertase 9IBA
11/2016
1GlypicansIBA
11/2016
1peptide AIBA
01/2015
1Antineoplastic Agents (Antineoplastics)IBA
05/2014
1tetrapeptide carbamateIBA
05/2014
1AcidsIBA
01/2014
1Shiga Toxin (Shigella Toxin)IBA
01/2014
1Tetrazolium SaltsIBA
01/2014
1Messenger RNA (mRNA)IBA
01/2014
1Catalytic RNA (Ribozymes)IBA
01/2014
1ErbB Receptors (EGF Receptor)IBA
11/2012
1LipopolysaccharidesIBA
04/2012
1CytokinesIBA
04/2012
1LDL Lipoproteins (beta Lipoproteins)IBA
10/2009
1LDL CholesterolIBA
10/2009
1LigandsIBA
10/2009
1Epidermal Growth Factor (EGF)IBA
10/2009
1ApolipoproteinsIBA
10/2009
1N'- (3,4- dihydroxybenzylidene)- 3- hydroxy- 2- naphthahydrazideIBA
10/2009
1Pharmaceutical PreparationsIBA
07/2008
1ExotoxinsIBA
07/2007
1anthrax toxin (anthrax lethal factor)IBA
07/2007
1Glucose (Dextrose)FDA LinkGeneric
03/2007
1Blood Glucose (Blood Sugar)IBA
03/2007
1Insulin (Novolin)FDA Link
03/2007

Therapy/Procedure

2Therapeutics
01/2014 - 07/2007